Overall survival after pelvic exenteration for gynecologic malignancy

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Pelvic Exenteration in Gynecologic Cancer

Background: Pelvic exenteration is an ultraradical surgery involving the en bloc resection of the pelvic organs, including the internal reproductive organs, the distal urinary tract (ureters, bladder, urethra), and/or anorectum. It is mainly applied as a salvage surgery for recurrent gynecologic tumors of any origin (vulva, vagina, cervix, uterine, and also ovary). Our aim was to establish the ...

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Total Pelvic Exenteration for Gynecologic Malignancies

Total pelvic exenteration (PE) is a radical operation, involving en bloc resection of pelvic organs, including reproductive structures, bladder, and rectosigmoid. In gynecologic oncology, it is most commonly indicated for the treatment of advanced primary or locally recurrent cancer. Careful patient selection and counseling are of paramount importance when considering someone for PE. Part of th...

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Survival after pelvic exenteration for uterine malignancy: A National Cancer Data Base study.

OBJECTIVE To determine overall survival (OS) and factors associated with OS after pelvic exenteration for uterine cancer. METHODS Women with uterine cancer who underwent exenteration (n=1160) were identified from the 1998-2011 National Cancer Data Base. Kaplan-Meier and multivariate Cox proportional-hazards survival analyses were performed to test for associations of potential explanatory var...

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Determinants of survival following pelvic exenteration for primary rectal cancer.

BACKGROUND Pelvic exenteration is a potentially curative treatment for locally advanced primary rectal cancer. Previous studies have been limited by small sample sizes and heterogeneous data. A consecutive series of patients was studied to identify the clinicopathological determinants of survival. METHODS All patients undergoing pelvic exenterative surgery for primary rectal cancer (1992-2014...

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Pelvic Exenteration: Surgical Approaches

Although the incidence of local recurrence after curative resection of rectal cancer has decreased due to the understanding of the anatomy of pelvic structures and the adoption of total mesorectal excision, local recurrence in the pelvis still remains a significant and troublesome complication. While surgery for recurrent rectal cancer may offer a chance for a cure, conservative management, inc...

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ژورنال

عنوان ژورنال: Gynecologic Oncology

سال: 2014

ISSN: 0090-8258

DOI: 10.1016/j.ygyno.2014.06.034